Congenital Diaphragmatic Hernia (CDH) is a condition in which a hole in the diaphragm allows abdominal organs to move into the chest and restrict lung development. Congenital diaphragmatic hernia (CDH) is a birth defect that occurs in about one in every 2,500 live births.
It is characterized by the development, very early in gestation, of a hole in the diaphragm, the breathing muscle that separates the chest from the abdomen. The hole occurs most commonly on the left side.
As a result, the intestines and other organs in the abdomen can move into the chest and compress the developing lungs. This prevents the lungs from growing and developing normally, which can cause reduced blood flow to the lungs and pulmonary hypertension (high blood pressure in the pulmonary circulation).
It can be life-threatening unless treated.